James Best returns as the boat captain in this sequel to the original B-movie. John Schneider is also in it.

From http://roberthood.net/blog/index.php...killer-shrews/

Filmed by independent regional film company Hollywood Pictures Corporation to be released as part of a double feature with The Giant Gila Monster (US-1959), The Killer Shrews was made for an estimated $123,000 and made a reported $1,000,000 in the US — not counting DVD sales since, I assume (IMDb). It frequently appears in lists of the worst films of all time, yet people seemed to like it…

Now, we have Return of the Killer Screws, co-written (with Pat Moran) and directed by Steve Latshaw, hoping to recreate the exploitation enjoyment of the original for a new generation of B-horror fans while pushing the technical quality up a few notches. In a production driven by the original film’s main star, Latshaw gets to direct James Best in his reboot; Best will be recreating the role he made “famous” in the 1959 late-night classic.
If you missed the original Attack Of The Killer Shrews, you can watch it free at the link above about the sequel. Or you can watch it with some help from Joel, Tom Servo and Crow of Mystery Science Theater 3000. It's an extremely funny episode.
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This Killer Shrew concept art looks a lot like Warhammer Skaven!